AmpliTube 5 (IK Multimedia) and Guitar Rig 7 Pro (Native Instruments) are the two most established software amp-and-effects racks, and guitarists shopping for a plugin rig almost always end up weighing them against each other. They aim at the same job from opposite philosophies: AmpliTube is a catalog of officially licensed real-world gear, while Guitar Rig is a modular tone-shaping workshop.
Decisive signal
The decisive split is authenticity versus modularity. AmpliTube licenses named amps and pedals from Fender, Mesa/Boogie, Ampeg, Fulltone and others, so you are dialing in specific real hardware, and its four-amp routing plus a genuinely useful room-and-mic section make it the stronger tool for accurate re-amping and bass tone. Guitar Rig 7 answers with Intelligent Circuit Modeling (ICM), a machine-learning approach whose four new amps finally sound alive and dynamic, but its real edge is a freely reorderable rack packed with lo-fi and modulation modules that abuse vocals, synths and drum buses as happily as a guitar DI. One is a licensed-gear collection; the other is a sound-design playground that happens to include amps.